Description
Product Characteristics:
Aliases: ruvC antibody, b1863 antibody, JW1852 antibody, Crossover junction endodeoxyribonuclease RuvC antibody, EC 3.1.22.4 antibody, Holliday junction nuclease RuvC antibody, Holliday junction resolvase RuvC antibody
Target Information: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. {ECO:0000269:PubMed:1661673, ECO:0000269:PubMed:1758493}